aPTT in children receiving UFH: time for a change?
نویسندگان
چکیده
منابع مشابه
aPTT in children receiving UFH: time for a change?
Unfractionated heparin (UFH) remains an important therapeutic modality for anticoagulation in children. Its short half-life and easy reversibility with protamine sulfate make it an attractive option in critically ill children. Although initially described as a screening tool for hemophilia, the aPTT is a global hemostatic assay that reflects the integrity of the intrinsic and common pathways of...
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Lack of correlation between heparin dose and standard clinical monitoring tests in treatment with unfractionated heparin in critically ill children.
UNLABELLED The activated partial thromboplastin time (aPTT) and anti-Xa activity are used for monitoring unfractionated heparin (UFH) therapy in children and may not be optimal. OBJECTIVE Determine correlations of aPTT, anti-Xa and UFH dose in children. Single centre prospective cohort study in children receiving UFH. The aPTT and anti-Xa results from routine coagulation monitoring were colle...
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ژورنال
عنوان ژورنال: Blood
سال: 2015
ISSN: 0006-4971,1528-0020
DOI: 10.1182/blood-2015-08-664037